The AU team
The research team at Molecular Biology and Genetics (AU) is led by professor Poul Nissen and utilizes X-ray crystallography to explore the structure and function of biomolecules. As crystallization of proteins requires high purity and fairly large amounts, we can also with expression and purification of difficult targets, including membrane proteins.
The team is located at the Section for Structural Biology within the Department of Molecular Biology and Genetics, and is part of DANDRITE, the Danish node of the Nordic EMBL Partnership for Molecular Medicine.
The researchers at DANDRITE investigate the molecular mechanisms that control the signalling and communication pathways in the brain and nervous system. These are of great importance for behaviour, senses and consciousness, as well as for neurological and psychiatric conditions such as Alzheimer’s disease, Parkinson’s disease, epilepsy, depression and schizophrenia.
DANDRITE stands for “The Danish Research Institute of Translational Neuroscience”, and plays on the word ”dendrite”, the network structure of nerve cells. Translational neuroscience encompasses that we aim for translating the new knowledge into new strategies in diagnostic and clinical practice for neurological and psychiatric diseases, as well as drug discovery and spin-out activities.