Small-angle scattering2018-02-28T16:24:10+01:00

Small-angle scattering

Small-angle scattering provides structural information from the nanometer regime to the micrometer regime. This can be applied to a wide range of samples, proteins, protein complexes, polymers, emulsions, colloids and nanoparticles. Depending on the samples, either small-angle X-ray scattering (SAXS) or small-angle neutron scattering (SANS) can be used.

The figure demonstrates the basic setup of a small-angle scattering experiment. A beam of X-rays or neutrons enters the experimental setup in the lower right corner. It is then collimated and directed onto the sample of interest. The beam scatters from the sample and the scattering is recorded on an area detector.

The resulting data is integrated over the detector and usually presented as a plot of scattering angle vs. scattering intensity (q), as demonstrated in the upper right of the figure above. From this scattering pattern, information regarding the shape, size, flexibility and interactions of particles can be extracted.

Illustration provided by Nicholas Skar-Gislinge.

The figure demonstrates the basic setup of a small-angle scattering experiment. A beam of X-rays or neutrons enters the experimental setup in the lower right corner. It is then collimated and directed onto the sample of interest. The beam scatters from the sample and the scattering is recorded on an area detector.

The resulting data is integrated over the detector and usually presented as a plot of scattering angle vs. scattering intensity (q), as demonstrated in the upper right of the figure above. From this scattering pattern, information regarding the shape, size, flexibility and interactions of particles can be extracted.

The Niels Bohr Institute team Copenhagen University

The research team at the Niels Bohr Institute led by professor Lise Arleth utilizes the technique small-angle scattering to characterize the samples provided by the collaborators.

Lise Arleth
Lise ArlethLINX Scientific Director, Professor.
University of Copenhagen
Niels Bohr Institute
Universitetsparken 5, D308
Dk – 2100 København Ø
Denmark

E-mail: arleth@nbi.ku.dk
Tel.: +45 3533 4795

Erik Brok
Erik BrokLINX Branch Manager, Ph.D.
University of Copenhagen
Niels Bohr Institute
Universitetsparken 5, D308
Dk – 2100 København Ø
Denmark

E-mail: e.brok@nbi.ku.dk
Tel.: +45 5090 8137

Gregory Smith
Gregory SmithLINX Project Leader, Ph.D.
University of Copenhagen
Niels Bohr Institute
Universitetsparken 5, D308
Dk – 2100 København Ø
Denmark

E-mail: gregory.smith@nbi.ku.dk
Tel.: +45 3533 5823

Martin Schmiele
Martin SchmieleLINX Project Leader, Ph.D.
University of Copenhagen
Niels Bohr Institute
Universitetsparken 5, D308
Dk – 2100 København Ø
Denmark

E-mail: martin.schmiele@nbi.ku.dk
Tel.: +45 5020 6570

Read more about The LINX Team.